Abilify. Dosage, Side Effects, Interactions
ABILIFY contains the active substance aripiprazole and belongs to a group of medicines called antipsychotics. It is used to treat adults and adolescents 15 years and older who have a condition characterized by symptoms such as hearing, seeing or feeling things that are not there, suspiciousness, delusions, incoherent speech, disorganized behavior and flattened mood. People with this condition may also feel depressed, feel guilty, anxious, or tense.
ABILIFY is used in adults and adolescents 13 years and older to treat a condition of feeling excessively high, feeling like you have excess energy, needing much less sleep than usual, talking very quickly with rapidly changing ideas, and sometimes severe irritability. In adults, it also prevents this condition from coming back in patients who have responded to treatment with ABILIFY.
How to take and dosage of Abilify
Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
The recommended dose for adults is 15 mg once a day. However, your doctor may prescribe you a lower or higher dose up to a maximum of 30 mg once a day.
Children and adolescents
This medicine can be started with the oral solution (liquid) at a low dose. The dose can be gradually increased to the recommended dose for adolescents of 10 mg once a day . However, your doctor may prescribe you a lower or higher dose up to a maximum of 30 mg once a day.
If you have the impression that the effect of ABILIFY is too strong or too weak, talk to your doctor or pharmacist.
Try to take ABILIFY at the same time every day. It doesn’t matter if you take them with food or on an empty stomach. Always take the tablet with water and swallow it whole.
Even if you feel better, do not change or stop your daily dose of ABILIFY without first asking your doctor.
If you take more ABILIFY than you should
If you find you have taken more ABILIFY than your doctor has recommended (or if someone else has taken your ABILIFY), contact your doctor right away. If you cannot reach your doctor, go to the nearest hospital and take the pack with you.
The following symptoms have occurred in patients who have taken too much aripiprazole:
rapid heartbeat, restlessness/aggressiveness, speech disorders
unusual movements (especially of the face or tongue) and decreased level of consciousness.
Other symptoms may ibclude :
acute confusion, seizures (epilepsy), coma, a combination of fever, faster breathing, sweating,
Muscle stiffness and lightheadedness or sleepiness, slower breathing, shortness of breath, high or low blood pressure, abnormal heart rhythms.
Tell your doctor or a hospital straight away if you have any of the side effects listed above.
If you forget to take ABILIFY
If you miss a dose, take the missed dose as soon as you remember, but do not take a double dose in one day.
If you stop taking ABILIFY
Don’t stop your treatment just because you feel better. It is important that you continue to take ABILIFY for as long as your doctor has told you to.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
Side effects of Abilify
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Common side effects (may affect up to 1 in 10 people):
diabetes (diabetes mellitus),
feeling restless and unable to keep still, difficulty sitting still
akathisia (an uncomfortable feeling of restlessness and a compulsive need to move),
uncontrollable twitching, twitching or writhing movements,
tremors and blurred vision,
constipation and indigestion,
more saliva in the mouth than normal,
Uncommon side effects (may affect up to 1 in 100 people):
increased or decreased levels of the hormone prolactin in the blood,
too much sugar in the blood
changed or increased sexual interest,
uncontrollable movements of the mouth, tongue and limbs (tardive dyskinesia),
a muscle disorder that causes writhing movements (dystonia)
sensitivity of the eyes to light,
a drop in blood pressure when you stand up, which can cause dizziness, lightheadedness or fainting,
The following side effects have been reported since marketing of oral aripiprazole, but the frequency with which they occur is not known:
low white blood cell count,
low level of blood platelets,
allergic reaction ( eg swelling of the mouth and throat, swelling of the tongue and face, itching, hives),
onset or worsening of diabetes (sugar sugar), ketoacidosis (excretion of ketones in the blood and urine) or coma,
high blood sugar,
decreased sodium level in the blood,
loss of appetite (anorexia),
suicidal thoughts, suicide attempt and suicide,
combination of fever, muscle stiffness, rapid breathing, sweating, decreased level of consciousness and sudden changes in blood pressure and heart rate, fainting (neuroleptic malignant syndrome)
serotonin syndrome (a reaction that can cause feelings of happiness, sleepiness, clumsiness, restlessness, feeling drunk, fever, sweating or stiff muscles),
fixation of the eyeballs in one position,
sudden unexplained death,
life-threatening irregular heartbeat,
Blood clots in the veins, particularly in the legs (symptoms include swelling, pain and redness in the leg) that travel through the blood vessels to the lungs, causing chest pain and difficulty breathing (if you notice any of these symptoms, seek medical advice immediately). ),
high blood pressure,
accidental inhalation of food with risk of pneumonia,
spasm of the glottis,
inflammation of the pancreas,
discomfort in the stomach,
yellowing of the skin and eyeballs,
reports of abnormal liver values,
skin sensitivity to light,
severe allergic reactions such as Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS). DRESS begins with flu-like symptoms and a rash on the face, followed by a spreading rash, high temperature, enlarged lymph nodes, increased levels of liver enzymes in blood tests, and an increase in a type of white blood cell (eosinophilia)
Unusual muscle failure that can lead to kidney problems (rhabdomyolysis)
unwanted urination (incontinence),
withdrawal symptoms in newborns, when used during pregnancy,
prolonged and/or painful erection,
Difficulty controlling core body temperature or overheating
swelling of hands, ankles or feet,
For blood tests: increased or fluctuating blood sugar levels, increased levels of glycated hemoglobin,
Inability to resist the impulse, drive, or temptation to do certain things that could harm you or others, eg.:
gambling addiction, regardless of serious personal or family consequences,
Changed or increased sexual interest and behavior that seriously disturbs you or others, eg an increased sex drive,
uncontrollable compulsive buying or spending,
Binge eating (eating large amounts in a short period of time) or compulsive eating (more than normal and beyond satiety),
a tendency to wander (without aim).
Tell your doctor if you experience any of these behaviors. He/She will discuss with you how these symptoms can be controlled or reduced.
More deaths have been reported in elderly patients with dementia while taking aripiprazole. Cases of stroke or temporary hypoperfusion of the brain have also been reported.
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