Klonopin (Clonazepam)

$ 149.16$ 948.79

Category: Anti-Anxiety
Commercial name: Klonopin, Rivotril
Active ingredient: Clonazepam
Production form: Pills
Available dosage: 0,5mg, 1mg, 2mg

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Description

Klonopin (Clonazepam): Dosage, Side Effects, Interactions

What is Klonopin and how is it used?

Klonopin is a prescription drug used to treat the symptoms of seizures and panic disorder. Klonopin can be used alone or with other medications.

Klonopin belongs to a class of drugs called Antianxiety Agents, Anxiolytics, Benzodiazepines, Anticonvulsants, Benzodiazepines.

Klonopin, a benzodiazepine, is available as scored tablets with a K-shaped perforation containing 0.5 mg of clonazepam and ungraded tablets with a K-shaped perforation containing 1 mg or 2 mg of clonazepam. Each tablet also contains lactose, magnesium stearate, microcrystalline cellulose and corn starch

What are the possible side effects of Klonopin?

Klonopin can cause serious side effects, including:

  • new or worsening seizures,
  • severe drowsiness,
  • unusual mood or behavior changes,
  • Confusion,
  • Aggression,
  • hallucinations,
  • thoughts of suicide or harming yourself
  • weak or shallow breathing,
  • pounding heartbeats or fluttering in the chest, and
  • unusual or involuntary eye movements

The most common side effects of Klonopin are:

    • feeling tired or depressed
    • Sleepiness,
    • Dizziness,
    • memory problems and problems with balance or coordination

INDICATIONS

Seizure disorder

Klonopin is useful alone or as an adjunct in the treatment of Lennox-Gastaut syndrome (petit mal variant), akinetic and myoclonic seizures. Klonopin may be useful in patients with petit mal seizures who have not responded to succinimide.

Panic disorder

Klonopin is indicated for the treatment of panic disorder with or without agoraphobia as defined in DSM-V. Panic disorder is characterized by the onset of unexpected panic attacks and associated concern about additional attacks, concern about the effects or consequences of the attacks, and/or a significant change in behavior associated with the attacks.

DOSAGE OF KLONOPIN (CLONAZEPAM)

Clonazepam is available as a tablet. The tablets should be taken with water by swallowing the tablet whole.

Seizure disorder

Using multiple antiseizure drugs can increase the side effects of CNS depressants. This should be considered before adding Klonopin to an existing anticonvulsant.

Adults

The starting dose for adults with seizure disorders should not exceed 1.5 mg/day divided into three doses. The dosage may be increased in increments of 0.5 to 1 mg every 3 days until seizures are adequately controlled or until side effects preclude further increase. The maintenance dose must be individualized for each patient based on their response. The maximum recommended daily dose is 20 mg.

Pediatric Patients

Klonopin is administered orally. To minimize drowsiness, the starting dose for infants and children (up to 10 years or 30 kg body weight) should be between 0.01 and 0.03 mg/kg/day, but not exceeding 0.05 mg/kg/day for two or three divided doses. Dosing should be increased by no more than 0.25 to 0.5 mg every third day until a daily maintenance dose of 0.1 to 0.2 mg/kg body weight is reached unless seizures are controlled or side effects are closing another increase. Whenever possible, the daily dose should be divided into three equal doses. If doses are not evenly spaced, the largest dose should be administered prior to retirement.

Panic disorder

Adult

The starting dose for adults with panic disorder is 0.25 mg bid. An increase in the target dose for most patients from 1 mg/day can occur after 3 days. The recommended dose of 1mg/day is based on the results of a fixed dose study where the optimal effect was observed at 1mg/day. Higher doses of 2, 3, and 4 mg/day in this study were less effective than the 1 mg/day dose and were associated with greater side effects. Nonetheless, it is possible that some individual patients may benefit from doses up to a maximum of 4 mg/day, and in these cases the dose may be increased in increments of 0.125 to 0.25 mg every 3 days until panic disorder is controlled or until side effects cause further undesirable increases.

Treatment should be discontinued gradually with a decrease of 0.125 mg bid every 3 days until the drug is completely withdrawn.

There is no evidence as to how long the patient treated with clonazepam should remain on it. Therefore, the physician who decides to use Klonopin for a longer period of time should periodically re-evaluate the long-term usefulness of the drug for the individual patient.

Pediatric Patients

There is no clinical study experience with Klonopin in patients under 18 years of age with panic disorder.

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Additional information

Dosage

2 mg

Quantity

30, 60, 90, 120, 180, 270, 360

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